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Animal Facility

Summary

The ADA Forsyth Institute maintains an animal facility to support the Institute’s mission of performing cutting edge research in oral and craniofacial biology. The facility has been in operation since the mid 1960s, when it housed one of the earliest germ-free rodent housing systems. The ADA Forsyth Animal Facility supports the Institute’s work on the forefront of work on the human microbiome, as well as research efforts in oral immunology and mineralized tissue biology.

The current facility occupies a total of 3650 sq ft, including animal holding rooms, procedure spaces, cage wash, IVIS imaging and a germ-free facility. All animals are maintained under SPF conditions, with a sentinel program in place for mouse housing. The facility has been fully accredited by AAALAC since 1977, is registered with USDA and maintains an assurance with PHS. The facility complies with all USDA, OLAW and City of Cambridge requirements.

The animal program is overseen by the Forsyth IACUC, which performs protocol approval and program oversight for both internal and external projects. The IACUC meets six times per year. Contact us at IACUC@forsyth.org. ADA Forsyth endorses the use of the ARRIVE guidelines for reporting animal research.

Mission

The animal care program at ADA Forsyth exists to support the research endeavors designed to promote the ADA Forsyth mission.

Services Offered:

  • Housing and care of mice and rats
  • ADA Forsyth personnel provide full husbandry services including cage caging and washing, feeding, watering and daily care related to husbandry
  • Health surveillance and diagnostic services
  • Other items available include basic lab equipment including biosafety cabinets, microscopes, weighing scales and other equipment

Equipment

  • Surgical rooms
  • Holding rooms
  • Procedure rooms
  • Surgical microscope
  • Germ-free facility
  • IVIS and CellVizio imaging units

Additional Information

All animals are maintained under SPF conditions, with a sentinel program in place for mouse housing. The facility has been fully accredited by AAALAC since 1977, is registered with USDA and maintains an assurance with PHS. The facility complies with all USDA, OLAW, and City of Cambridge requirements. The animal program is overseen by the Forsyth institutional animal care and use committee (IACUC), which performs protocol approval and program oversight for both internal and external projects. The IACUC meets six times per year.

Policies

Administration of Analgesia  – Download
Aseptic Surgery  – Download
Training of New Staff – Download
Protocol Approval Levels – Download
Blood Collection – Download
Designated Member Review –Download
Environmental Enrichment – Download
Euthanasia Policy Statement – Download
Evacuation of Animal Facility – Download
Humane Endpoints –Download
Increase in Mouse Numbers –Download
Minimizing the Number of Animals Used – Download
Outside Animal Work –Download
Photography in the Animal Facility – Download
Principal Investigators – Download
Pilot Studies Policy – Download
Putative Oral Pathogen – Download
Reporting Adverse Events – Download
Rodent Injection – Download
Social Housing – Download
Use of Cell Lines and Other Biological Materials in Animals – Download
Use of Non-Pharmaceutical Grade Compounds – Download
Virtual IACUC Meetings – Download
Visitor Policy – Download
VVC Injections –Download
VVC Strains –Download

Contact

iacuc@forsyth.org

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